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Indian J Exp Biol ; 1993 Mar; 31(3): 235-7
Article in English | IMSEAR | ID: sea-58072

ABSTRACT

The psychoactive drugs imipramine, chlorpromazine and lithium chloride inhibit tryptamine tetrazolium reductase activity in vitro by 68, 60 and 33% respectively at a concentration of 1 x 10(-3) M while amphetamine negligibly inhibits the enzyme activity. No change in enzyme activity is observed in vivo.


Subject(s)
Animals , Brain/drug effects , Chlorides/pharmacology , Chlorpromazine/pharmacology , Dextroamphetamine/pharmacology , Imipramine/pharmacology , Lithium/pharmacology , Lithium Chloride , Male , Oxidoreductases Acting on CH-NH Group Donors/antagonists & inhibitors , Psychotropic Drugs/pharmacology , Rats
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